The Curse Has Fallen revolves around Klaus Ashford, a high school student living in the town of Bayview. Klaus becomes the eponymous teenage werewolf after he is bitten by a werewolf on the first night of his second year of high school, drastically changing his once-ordinary life. The bite forces him to balance his new identity with his day-to-day teenage life and eventually help protect his hometown, which he learns is a beacon for supernatural activity.