The promise of biotech has been realised. Death, disease, frailty, all things of the past... if you can afford to upgrade. The one thing technology hasn't been able to cure is The Sterility. The last human birth was over thirty years ago. Carlton Smalls, the last human being ever to be born, just wants to live his life, but when he reluctantly accepts an invitation for an upgrade consultation, he soon finds himself running through a dangerous world he never knew existed.