Wolfe is Dean's four-year-old daughter, her mother didn't want her when she was born, so Dean has been raising her alone. His brother Sam and his dad helped a lot for the first two years, but now Sam's been away for two years. Sam and Dean's father has been missing for almost a month now and Dean needs his right-hand man, best friend, baby brother, and free babysitter back. So he and Wolfe head out to Stanford to get him.