When his sister, Olive, disappeared one night Tony Stark had hopes he would see her again one day. As the years went on that hope faded to nothing until 27 years later when she finally returns.
With his aunt gone, Peter doesn't stop until he gets to the bottom of who actually murderer his aunt in cold blood. He doesn't stop even when things takes a turn as more secrets unfold.
Natasha Romanoff thought her past was gone until Yelena Belova disappeared. Her and Clint scoured the Earth trying to find her and what had rebuilt. That was until day of Peter's decathlon competition.