This comprehensive handbook offers a practical guide for K-12 teachers in the Philippines navigating the transition between face-to-face and online/distance learning. It delves into the specifics of the DepEd K12 curriculum, emphasizing successful pedagogical strategies for each age group, culturally responsive teaching, and the management of both physical and virtual classrooms. With a special focus on online platforms like Zoom, it provides best practices for online teaching and assessment. The handbook also discusses the vital role of teachers in supporting student well-being, effective communication with parents, and opportunities for professional development. With legal and ethical considerations for educators, this guide is an essential resource for modern, digital-savvy educators.