After a failed marriage, a broken heart and a load of trust issues, Rishabh Luthra, one of the most successful business tycoons in the city, decides to no longer get married and indulge himself in business matters and his family only. Born in the Singhania family who's known for their powerful and influential position in the business kingdom, Ishika Singhania has only one aim: to become the most successful businesswoman and overtake the rivals, the Luthras. Rishabh, an introvert, always follows the conventional approach and loves to follow the accepted way. Meanwhile Ishika, always goes for the 'smart work makes the dream work' approach, takes risks and enjoys life with her extroverted nature. What will happen when these two polar opposites meet each other? Will it lead to a war or will this be the start of a 'Serenade of Hearts'?