Shinobi, Dragons, and Heroes vs Reapers

Naruto Uzumaki, Issei Hyoudou and Izuku Midoriya Great heroes in their respective worlds. Naruto Uzumaki-Namikaze is the son of the Late Greats Minato Namikaze and Kushina Uzumaki and twin brother of Naruko Uzumaki during the 4th Shinobi War Naruto was able to defeat Sasuke, Madara, and Kaguya but Naruto fell into a portal.

Issei Hyoudou during the fight with Trihexa Issei defeated Rizevam before Sirzechs and the others could seal themselves but then was sent to another dimension within the Dimensional Gap.

Izuku Midoriya after defeating the LOV he and secret fiancé Momo Yaoyorozu were enjoying themselves that was when he was betrayed by classmates and left for dead, but Izuku survives as he was sent through a portal thanks to Kurogiri.

the Three heroes find themselves in a whole new world with different dangers as Naruto, Issei, and Izuku join the Alliance Military becoming Humanities strongest members as they are scouted by the Council to become Spectres.

The Trio joins the Normandy to stop Saren but unknown to them that Saren was the just the beginning of what's to come.

Disclaimer: I do not own Mass Effect, Naruto, Highschool DxD, and My Hero Academia