Airing on The CW, the young adult animated dramedy series centers on a group of mismatched teenage cells from different school cliques; Osmosis Jones, Drix Koldreliff, Maria Amino, Leah Estrogen, Conscious Santorini, Aaliyah Estrogen, Drixteen, Dixie Estrogen, Cillia Tyson, Twyla Estrogen, Cole Myosin, Brittany Estrogen, and Paul Spryman. After defeating a scarlet fever bacterium before prom night, the cells begin living double lives as spies, vowing to protect their city against germs and viruses and face the perils of teenage life.