Defeat Cancer through Therapy
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  • Reads 2
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  • Parts 1
  • Time <5 mins
Ongoing, First published Feb 12, 2024
CAR T cell therapy, a groundbreaking form of immunotherapy, is revolutionizing cancer treatment. This innovative therapy harnesses the power of the body's immune system to target and destroy cancer cells.

CAR T cell therapy involves genetically modifying a patient's own T cells to recognize and attack cancer cells. This process begins with the collection of the patient's T cells through a process called leukapheresis. These T cells are then genetically engineered in a laboratory to express chimeric antigen receptors (CARs) on their surface. These CARs enable the T cells to recognize specific proteins, or antigens, found on the surface of cancer cells.

Once the CAR T cells have been engineered, they are expanded in the laboratory to generate a large population of cancer-fighting cells. These modified CAR T cells are then infused back into the patient's bloodstream, where they can seek out and destroy cancer cells throughout the body.

CAR T cell therapy has shown remarkable success in the treatment of certain types of blood cancers, such as leukemia and lymphoma. Patients who have failed to respond to traditional treatments, such as chemotherapy or stem cell transplantation, have experienced dramatic and often long-lasting remissions following CAR T cell therapy.

Despite its remarkable efficacy, CAR T cell therapy also comes with potential risks and side effects, including cytokine release syndrome (CRS) and neurotoxicity. These side effects can range from mild to severe and require careful management by healthcare professionals.

As research in CAR T cell therapy continues to advance, scientists are exploring its potential applications in treating other types of cancer, including solid tumors. With ongoing innovation and improvements in technology, CAR T cell therapy holds immense promise as a transformative approach to cancer treatment, offering hope to patients facing even the most challenging diagnoses.
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