Why doth thou appeal to me so much so?

Anxiety, Depression, Desolation, Self-hatred,...Do our feeble and insignificant human lives even have any meaning left in them if we fail to live up to our own expectations, our wants, our desires, our ambitions and our dreams that inadvertently lead us to lose our key to happiness? Is it even worth it to stay alive in circumstances such as these? Or is it our divine duty as human beings, as the so-called 'chosen ones' to strive to keep living on our lives no matter what the circumstances may be? I wonder.