Plasma Protein Binding Assay

https://axispharm.com/plasma-protein-binding-assay/

The plasma protein binding assay measures the proportion of compounds that are not bound (free) to the protein in the plasma by equilibrium dialysis. Since only the free compound can bind to its target and produce activity, and the compound bound to plasma protein may have a longer half-life and lower clearance rate, the determination of plasma protein binding rate is very important for understanding the activity of the compound and tissue distribution.