A disease was discovered from many years ago, they call this the "Missing Puzzle Disease" or MPD in short. Every Amurta graduates and students have had multiple attempts on trying to find a cure. But no medicine helped. Instead, they found an alternative from medicine that worked. They thought it was finally their answer. But in reality, it was just a temporary solution to hindrance the disease. Now in modern time, Kaveh and Alhaitham are trying to find their missing piece.