Into the Unknown - {supernatural crossover}

Sydney Winchester, twin sister of Dean Winchester, has a sharp wit and a quick, sharp tongue, which tends to get her in trouble half the time. Despite having grown up hunting monsters with her family, Sydney chose to pursue her path in life and become a surgeon. This decision proved to be a tension between her and her father, John Winchester, who wanted Harley to continue the family tradition of hunting. With tensions high between herself and her father, Sydney decides to run away and start a new life away from the neglectful childhood she once knew. With the heartwrenching decisions, Sydney decides to leave the comfort of having her two siblings left behind. She pulls it together and realizes this is what she wants to do. She works crappy jobs putting herself through college and Med school before ending up at Seattle Grace. In the same intern class as Meridith Grey. Where will her new life lead her? And will she ever be able to put the past in the past truly, or will it one day come back to bite her in the ass.

(You don't have to have a vast knowledge of either show to read. I try to go into as much detail as I can to make it enjoyable for everyone!)