Clinical Application and Advantages of Cryoablation for Bone Cancer

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The skeleton is the third most common site for cancer cell metastasis after the lungs and liver. Almost all malignant tumors can metastasize to the bones, accompanied by various serious complications. Among the comprehensive treatment methods for tumors, surgical resection remains the most effective measure, but it may leave residual tumor cells in the surgery area, potentially leading to postoperative recurrence. In such cases, cryoablation for bone cancer has made significant progress, promising long-term disease control and symptom relief.
The Mechanism of Cryoablation for Bone Cancer
Cryoablation for bone cancer utilizes the tip of an ultra-cold surgical instrument. When room temperature, high-pressure argon gas(coolant) is delivered, the tip rapidly freezes the diseased tissue to below -100℃ within seconds (coolant). When room temperature helium gas(heat medium) is delivered, the tip quickly heats the frozen diseased tissue, causing the target area cells to burst. Repeating the freeze-thaw process twice can rupture and destroy tumor cells within the target area, damage and thrombose microvascular endothelial cells, and reverse tumor immunosuppression.