Glyburide and Metformin HCl, sold under the generic name Glucovance, is a combination oral medication used to manage Type 2 Diabetes. This drug combines two different mechanisms to help control blood sugar levels: Glyburide: A sulfonylurea that stimulates the pancreas to produce more insulin. Metformin HCl: A biguanide that decreases glucose production in the liver and improves the body's insulin sensitivity.All Rights Reserved