Ethan Winters gets a mysterious message from his thought to be dead wife Mia Winters, telling him to save her from a random farm in the middle of Louisiana. Dumbfounded, confused, and beyond concerned for his wife's well-being, Ethan quickly takes a trip to the farm, but not before grabbing his younger sister along the way. Ivy Winters is a sarcastic, wild, and fiery fighter from hell, and nothing has ever scared her in the 24 years she's been alive. However, that all changes when she follows behind her brother on the mission to save her sister-in-law, only to encounter horrors beyond her imagination. Will Ivy be able to help her family survive, or will she succumb to the infection that seems to be rapidly spreading without anything stopping it?