As Medicare's new Prescription Payment Plan (MPP) launches in 2025, specialty pharmacies will play a crucial role in supporting patients with high-cost therapies by improving medication adherence and tracking outcomes. The MPP allows patients to spread their drug costs over the year, with a $2,000 annual cap. Specialty pharmacies can use outcome-tracking tools to monitor patient-reported outcomes (PROs) like symptom management and side effects, optimizing treatments and reducing hospital readmissions. By integrating financial guidance with outcome-tracking, these pharmacies can enhance patient engagement, improve adherence, and support the shift toward value-based care.