In this crossover between the Warhammer 40k universe and The Boys, When the Imperium of Man discovers Earth, they declare its inhabitants a lost colony of humanity. However, upon learning of the existence of Supes-mutated abominations granted unnatural abilities through Compound V-the Imperium deems them a dire heresy. The Adeptus Astartes, the Inquisition, and the Adepta Sororitas descend upon the planet, unleashing a holy purge unlike anything the world has ever seen.
Caught in the chaos, Billy Butcher and The Boys find themselves unlikely allies to the Imperium, joining the newly formed Ordo Supe Purge-a task force dedicated to exterminating every last Supe in the galaxy. Starlight, stripped of her illusions about heroism, takes up the mantle of a Sister of Battle, wielding divine fury against her former kind. Meanwhile, Hughie, Frenchie, and Mother's Milk are thrust into an intergalactic war where they must survive daemons, xenos, and the terrifying bureaucracy of the Imperium itself.
With Homelander facing his most powerful enemy yet-the Primarch Roboute Guilliman-the world watches as the war between false gods and true faith erupts in a brutal, blood-soaked crusade. But in a universe ruled by war and suffering, one thing remains clear:
No one hates Supes more than the Imperium of Man.