After Elaine's O'Malley's brother died, she decided that she's going to save lives... she's been friends with Meredith and Cristina for 2 years, she meets Mark who is heartbroken after Lexie chose Jackson...
Derek is an asshole with a whole lot of opinions on how the world should work. But then he runs into Meredith Grey and she turns everything on its axis. The two of them muddle through their feeling for each other as Derek finds out a lot more about his world.