Izaya and Roppi Orihara never did entirely see eye to eye. A relationship as toxic as can be. However one day Izaya's teasing goes to far, causing for the misanthrope to leave to her close friend Tsukishima Heiwajima, whom Roppi isn't aware that is madly in love with her and is willing to do anything to keep the misanthrope from going back with Ikebukuro's famous informant.