During a fateful car trip, the family of triplets Dagoberto, Damián, and David experiences a devastating accident, crashing in a nearby neighborhood. The consequences are catastrophic: both parents perish, Dagoberto is left paralyzed, and an unconscious David is flung from the car. Only Damián, who caused the accident, emerges unscathed.
Jaime, a man deeply scarred by the death of his own son, finds the barely alive David. Discovering his identity but exploiting the boy's complete amnesia regarding the accident and his family, Jaime decides to keep David, making him believe he is his father.
Despite everyone else believing David to be dead, his grandfather Calixto and Germán, the family's loyal butler and uncle to the triplets, refuse to give up hope. They tirelessly search for David, but as years pass, their hopes of finding him dwindle.
The only one who never loses hope of reuniting with his brother is Dagoberto, who grows into a kind-hearted man, though his disability makes him quite lonely. Damián, on the other hand, becomes an ambitious and manipulative man, who wants his brother to remain lost forever. David's return would mean sharing the inheritance, as well as the affection and attention of those around him, including his uncle Ramiro, for whom Damián harbors a twisted desire.
Inspired by the great telenovelas "Lazos De Amor" and "Tres Veces Ana," Three Paths, One Blood, promises a story filled with intricate family dynamics, deep emotional conflicts, and the timeless struggle between love and betrayal.