A disease that causes fatal bubbles to protrude all over a person's skin is spreading, and Vitrum City is its next target. Eleven-year old Miri Amith is determined to help everyone reach safety in the city before the protective dome encloses the city and isolates it from the outside world. When her mother does not make it to the dome in time, Miri blames herself as she helplessly watches her die. Wracked by guilt over her mother's death, she spends the next five years searching for a vaccine in the hopes that she can save others from dying in the same horrible manner. But finding the vaccine that could save millions of lives could mean putting her own life at risk.