As part of a malicious plot by Ares, Zeus and Hera trick the rest of the major Greek Gods into going down to Earth and posing as mortals. Only, they don't know they're pretending.
This is, of course, all in an attempt to get the mortals to once again worship the gods of old.
So it makes sense when the gods end up being some of the biggest up-and-comers in the film and music industries.
However, Zeus, Hera, and Ares hadn't put any thought into the idea that maybe their little messenger, Iris, would go down as well, with all of her memories intact, and with a mission of her own- to bring all of the expelled gods and goddesses back to Mt. Olympus, where they belong.