The girls face difficulties submitting the new governmental regulation of heroism forced on them. One day a stranger comes to them, asking for their help in order to protect a world-changing secret. They must find the long-lost ancient city of gold, Paititi and protect its most valued and cursed treasure, before the vicious Dick Dastardly finds it first. This time, who else would accompany them on their journey than the world's greatest adventurer, Captain K'nuckles and the ever-enthusiastic secret child agent, Numbuh Two.