Two years after the planets jeopardy by Sephiroth, Cloud lives separate and alone from most of the world, acting as a delivery man for his own Postal Company: Strife Delivery Service. Strife Delivery Service works with Tifa's 7th Heaven in caring for orphaned children infected with Geostigma Syndrome, a disease caused by Jenova's cells in the Lifestream that can result in severe pain or death.
When the planet is threatened again, Cloud finds himself carrying around the mistakes of his past, believing in his incapability a protecting anyone. Cloud's emmotional wounds allow him to be feint of heart, oppressed by the memories lost. Seeking forgiveness, he fights for the chance at redemption.
With the life of the planet at stake, Cloud fights on, battling his sins to save others. Cloud also struggles with his physical condition of being inflicted with Geostigma as well, which brings about painful memories of the past.
Sephiroth had wandered the lifestream, alone and not allowed to become part of the planet after his last death. He had resigned himself to wander forever, but he was offered the chance at redemption, with a catch. When the planet threw him a curveball, could he adapt and fulfill his assigned goal, or will he be destined to fail and never become part of the planet he had once tried to destroy.