The predictions made by the fanatical conspiracy theorists and doomsday preppers, wild as they were, turned out to hold more legitimacy than anyone wanted to think. As eighteen year old Sandra is on her way to school, she ignores the lectures about disaster preparedness made by her eccentric uncle, Dorian. Sandra endures yet another boring day at school, until her uncle's paranoid theories begin to unfold before her very eyes. With a new flu plaguing society and with cities being bombed by attackers unknown, Sandra and her friends flee the school, only to find that her Uncle Dorian is missing from her home. When the skies fall silent and when the town becomes empty, Sandra steps outside, intent on finding her uncle and ready to embark on a perilous journey to Dorian's legendary bugout location, a mysterious, secluded civilization called Sanctum.