In a way, we are all a little lost

In the year 2006, the Powerpuffgirls were defeated by the Rowdyruffboys. Mojo had finally conquered the city of Townsville, until scientists descovered a new substance similar to chemical X. Antidote X. Antidote X permanently removes the effects of chemical X. With the new, Antidote X, the Rowdyruffs were defeated and lost their powers, now in the year 2016, Brick is starting to realize that the effects of Antidote X aren't as permanent as everyone believes.