A young she-cat named Calypso faces in her youth terrible things, such as heart break and bullies. When she grows up she learns how to defend for herself, and helps out her friend Demas. But what she doesn't know that her life just gets even worse, Twolegs take cats and puts them in a cage and attaches tubes in them and does illegal experimenting. These normal cats turn into supernatural cats who gain unwieldy powers, some cats escape with their powers; others turn into the Changed. Calypso and Demas must find a way to get out or they will never be the same again.