Persistent genital arousal disorder (PGAD), originally called persistent sexual arousal syndrome (PSAS), Weiss Disease, and also known as restless genital syndrome (ReGS or RGS), results in a spontaneous, persistent, and uncontrollable genital arousal, with or without orgasm or genital engorgement, unrelated to any feelings of sexual desire. It was first documented by Dr. Sandra Leiblum in 2001, only recently characterized as a distinct syndrome in medical literature with a comparable counterpart increasingly reported by men.