The Last She-Wolf

Isabella was born as a vampire along with her brother Shiloh. Both Shiloh and Isabella were not your ordinary vampires though they had a mixture of powers of darkness that was gifted to them from a godly spirit long ago when they were babies.
Raised on an island and eventually stranded there Isabella "Bella" become known to humans across the world as "The Unknown" no one knew what they were exactly as a vampire species since they acted completely different.
Shiloh was oddly part dragon and was consumed more into the dark then Isabella. Isabella was just a vampire with the ability to control shadows and other objects.
Around the world there are other creatures. Werewolves were being hunted constantly and now there are no female werewolves left in the world... males still existed. Blood Moons are the time of biting and spreading lycanism "werewolf". This is the only way to have female werewolves repopulate.
Pirates sailed the seas and one particular one wanted to find Isabella "The Unknown".

""~the world of Aetheria~
There are pirates all throughout the world. Some seeking glory. Others seeking pride. Only one pirate has a different dream. His dream is to catch the rare and forbidden creature, the unknown. No one knows what this creature looks like yet they call it forbidden.......""