~Depression~

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A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.

Possible causes include a combination of biological, psychological, and social sources of distress. Increasingly, research suggests these factors may cause changes in brain function, including altered activity of certain neural circuits in the brain.

Depression can have a major impact on people's lives

Depression affects millions of people. Every patient is different and responds to treatment differently. For healthcare professionals seeking another option

Depression affects many...

MDD is the #1 contributor to disability worldwide5

MDD is the most common mental illness in the U.S., affecting almost 16 million adults6,7

In many different ways...

MDD is a heterogeneous disease—every patient can present with different symptoms8

Persistent depressed mood or loss of interest are common defining features of MDD*8

Other symptoms are also persistent and vary by patient8

Insomnia or hypersomnia

Weight gain or weight loss; increase or decrease in appetite

Psychomotor agitation or psychomotor retardation

Fatigue or loss of energy

Feelings of worthlessness or excessive/inappropriate guilt

Diminished ability to think/concentrate or indecisiveness

Recurrent thoughts of death/suicide or suicide attempt

Diagnosis of MDD requires five (or more) of the symptoms listed above, must be present for at least 2 weeks, and represent a change from previous functioning. At least one of the symptoms is either depressed mood or loss of interest or pleasure.



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