Lung Transplant In Delhi and Gurgaon, India
A lung transplant is a surgical procedure to replace a diseased or failing lung with a healthy lung, usually from a deceased donor. A lung transplant is reserved for people who have tried medications or ot...
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A lung transplant is a surgical procedure to replace a diseased or failing lung with a healthy lung, usually from a deceased donor. A lung transplant is reserved for people who have tried medications or other treatments, but their conditions haven't sufficiently improved.
Depending on the medical condition, a lung transplant may involve replacing one of your lungs or both of them. In some situations, the lungs may be transplanted along with a donor heart.
While a is a major operation that can involve many complications, it can greatly improve your health and quality of life.
History
Attempts at have occurred as early as 1946 when Vladimir Demikhov, a Soviet scientist, attempted single-lung transplantation in a dog. This transplant ultimately failed from bronchial anastomotic dehiscence, and difficulties with this anastomosis would plague clinical lung transplantation for the next 40 years. Henri Metras, in 1950, reported the first successful dog lung transplant and the first bronchial artery and left atrial anastomoses. In a nonhuman primate model, performed lung reimplantation and showed that these lungs were able to maintain function postoperatively, despite denervation. On June 11, 1963, reported the first human lung transplant; however, the patient died from kidney failure after 18 d. The first real survivor during this early era of lung transplantation was a patient of Fritz Derom's in Belgium.This patient, however, survived only 10 mo. The failure of this early experience in clinical lung transplantation can be summarized by inadequate immunosuppression and difficulties with the bronchial anastomosis.
The advent of cyclosporine brought about significant improvements in patient survival following liver and kidney transplantation. This led to a resurgence of interest in heart/lung transplantation in Stanford and lung transplantation in Toronto. The first successful combined heart–lung transplant was completed by Reitz and colleagues and showed that a grafted lung could survive and function in a recipient. Research performed by Cooper's group in Toronto showed that corticosteroid use appeared to be a significant factor in the weakness of the bronchial anastomosis. With the use of cyclosporine, corticosteroid use could be reduced, leading to improved bronchial healing. In 1986, the Toronto Lung Transplant Program reported the first successful single-lung transplantations for two patients with pulmonary fibrosis. This team went on to perform the first successful double-lung transplant, first with an en bloc technique that used a tracheal anastomosis, then evolving to the bilateral sequential transplantation technique that not only improved airway healing, but also had the additional benefit of avoiding cardiopulmonary bypass, if desired. This technique remains the standard technique in use to this day.
Indication
Lung transplantation is indicated for patients with chronic, end-stage lung disease who are failing maximal medical therapy, or for whom no effective medical therapy exists. General indications include:
