"when you play a video game too long"
That actually was on somebody's 1000 ways to die. Sitting for 3 days straight without using the bathroom slows the blood flow, and when you finally get up, the blood flow speeds up to a ridiculous rate and makes your heart explode. The heart was unable to process that amont of blood. Poeple say this really happened to a gamer.
... That sounds painfull....