Spider-Man Quits

Prologue

During the day

We see Spider-Man who was on top of the roof up as he was thinking about the damage Otto had done in his life as the superior Spider-Man and the relationships he had with the other superheroes whom he called friends.

The Avengers, X-Men, the defenders, the fantastic four and his own team the web warriors shut him out, Jessica and Susan banded him from seeing the kids.

Tony Stark Aka Iron-Man shut down Parker industries, Black Cat Felicia Hardy Everytime the see each other she would attack him.

And Mary Jane well you all already know that she left him for a guy named Paul.

So yeah with everything that's happened in his life Spider-Man finally had enough

Spider-Man: You know what new York you win.

Spider-Man aka Peter Parker went to a alley and took off his costume and puts it in trash and walks away never to be seen again.