If you feel depress try to help yourself. Let's think who else can help you other than you. If you feel that you are segregating from other let them be, just be yourself especially from your enemies.
Don't you ever think you are loser. If you feel lonely think that you are strong and don't need friend. If you have many friends take care the relationship. Appreciate the relationship. Keep the best relationship with the true and honest friend.
Try to help yourself. You can watch funny movies or inspire movies. Then relate your live to it.