Ghost type moves have no affect on Normal type Pokémon and vice versa. However, in the anime, during the Pokémon Advanced Generation season, a Shadow Ball attack (Ghost-type) was able to damage a Meowth (a Normal type Pokémon). No explanation for this is given. Also, Misty's Corsola damaged Cassidy's Sableye (a Dual Dark and Ghost-type Pokémon) with Spike Cannon.
