This one was requested a while ago so here I am with it
Mutation number one:
Your crush, Mark and Ethan are all werewolves because of a good story I've read recently. But you, Kat and Sam aren't
Mutation number two:
Splatoon edition. You get the idea
Mutation number three:
It's angel and devil style. Kat is a fallen angel, Mark is an angel, Ethan is an angel, Sam is a fallen angel, and you and you're crush are whatever you deem fit
Mutation number four:
Make it up.