Investments directed towards tourism development in a destination lead to the emergence of job openings for the local workforce, who subsequently secure employment in various establishments catering to tourists. This comprehensive study investigates the intricate relationship between socio-economic and socio-cultural factors and their impact on the well-being of 180 hotel employees within the dynamic tourism and hospitality sector. This study employed a descriptive research method, complemented by a range of statistical tools, including Frequency Distribution, Weighted Mean, ANOVA, and Linear Regression Coefficient of Correlation. These tools have been chosen to gather comprehensive information about the current conditions experienced by hotel employees and the extent to which the tourism and hospitality industries have influenced their social and economic well-being. The research presents a well-balanced demographic profile of employees, highlighting their generally positive perceptions of their roles, albeit with opportunities for enhancing their sense of belonging. Crucially, the study uncovers that hotel employees strongly associate their work environment with social development, economic stability, and multiculturalism, all of which exhibit substantial positive correlations with their overall well-being. These findings underscore the significance of adopting a holistic approach to employee well-being within the industry. Practical recommendations emphasize fostering a sense of belonging, promoting continuous learning and adaptability, and ensuring competitive compensation packages. Furthermore, the industry is encouraged to actively promote diversity and cultural integration to create an inclusive workplace. From a theoretical perspective, this research contributes to the literature by emphasizing the multifaceted nature of employee well-being in the context of socio-economic and socio-cultural factors.