First appearing during Shockwave's attack on Iacon city along with Astrotrain, Bludgeon, Brawl, Chopshop, Dirge, Frenzy, Octane, Onslaught, Ramjet, Tantrum, Venom and Vortex.

Blitzwing would appear again as one of the four Cybertronians needed by the Fallen for the unbinding.

During the civil war on Cybertron, Shockwave envisioned a Cybertronian with multiple alternate modes, studying Astrotrain and Blitzwing. However, the Great Shutdown meant his plans could go no further — until Unicron's servant Scourge located Cybertron and reactivated him for study. When Shockwave was attacked by Sharkticons Scourge saved him, only to be shot in the back by Shockwave. Shockwave then proceeded to examine and study him, using the secrets gleaned to create first the Duocons and then the Triple Changers — Astrotrain, Blitzwing, Octane and the Autobots Sandstorm and Broadside (interestingly, in the Micromasters mini-series by Dreamwave, Blitzwing and Astrotrain are suffering from severe physical changes. As this is before the Great Shutdown, this might imply that the change was a natural one rather than a result of experiments).

The Triple Changers then served as Shockwave's bodyguards, accompanying him to Earth to capture Optimus Prime and Megatron's troops, with Blitzwing taking down Megatron, leaving him vulnerable for a follow-up attack by Shockwave. Blitzwing was himself taken down by Grimlock. They were unable to prevent him from being stopped by Optimus Prime and Ultra Magnus back on Cybertron, but Astrotrain and Blitzwing accompanied Shockwave on his exile in the wastes of Cybertron, where his experiments resulted in Sixshot.