Neal Caffrey has visited New Orleans once before. In Voodoo Remoulade, a doubloon cursed by the pirate Jean Lafitte, along with a vampire nest, almost wrecked his plans to celebrate Mardi Gras. Sara's never been to New Orleans, and when Neal suggested taking her there to celebrate her birthday, he didn't expect lightning to strike twice. Peter probably wouldn't be so optimistic if only he knew about Neal's previous misadventure.
Pirates of Manhattan: https://www.wattpad.com/story/358317987-pirates-of-manhattan