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Here is top 8 of Y/N's major enemies:
1 - All For One - was exposed by All Might and Dabi as evil manipulator who chases selfish wishes, and wants to turn his brother figure into a new vessel.
2 - Hawks - was a hero spy who ignored Y/N's warnings and killed two of his friends, which made Y/N snap and massacre 24 innocent heroes, and because of him being a spy, Y/N's first operation completelly failed. And later after learning from Dabi that Hawks even mocked Twice for trusting him and treating him like a friend, Y/N's hatred towards him grew even more, and he promised to kill him no matter what.
3 - Overhaul - was making experiments on Eri, who was only 6 years old, which disgusted Y/N, who later teamed up with Heroes to defeat Overhaul in order to save Eri. Later when All For One ordered Y/N attack Tartarus, he also freed Overhaul, who alongside with Kurono massacred innocent workers and patients in hospital, when Y/N discovered this, he swored to kill Overhaul for good.
4 - Kurono - was Overhaul's right hand, who helped him in his awful actions.
5 - Katsuki Bakugo - used to bully Y/N for being quirkless and even almost drove him to suicide.
6 - Tomohito Kazari - also used to bully Y/N for being quirkless.
7 - Seiji Shishikura - killed Kasumi Minene, to somehow make Y/N suffer and even was ready to die with it.
8 - Edgeshot - from all pro heroes he was the one who confronted Y/N the most. Not once, not twice, but three times, and during third, and last confrontation was leader of heroes who defend Blackgate Prison.
