"Now I realize that there is no righteous path. It's just people trying to do their best in a world where it's far too easy to do your worst."

"You know, this world, this sad, doomed little world, it needs you. It needs every last Winchester it can get, and I will not let you die. I won't let any of you die. And I won't let you sacrifice yourselves. You mean too much to me, to everything."

"Maybe you could fight the mark for years. Maybe centuries, like Cain did. But you can't fight it forever. And when you turn, and you will turn, Sam, and everyone you know, everyone you love, they could be long dead. Everyone except me. I'm the only one who will have to watch you murder the world. So if there's even a small chance that we can save you, I won't let you out of this room."

"You're my family I love you, I love all of you. Just please... Please don't make my last moments be spent watching you die. Just run."

"You don't have to be ruled by fate. You can choose freedom. And I still believe that's something worth fighting for."

"What is so worth saving? I see nothing but pain here. I see inside you. I see your guilt, your anger, confusion. In paradise, all is forgiven. You'll be at peace. Even with Sam."