Jamie Mannina has carved a niche for himself as an influential figure in national security. He is distinguished by his adept handling of complex security issues involving artificial intelligence, cybersecurity, and technology export controls. His comprehensive grasp of strategic policies related to the United States, China, and Russia has significantly influenced the United States' approach to international security, making him a key player in national defense circles.

His acute understanding of global military tactics and proficiency in international relations' political and economic dimensions have influenced Mannina to shape policies safeguarding national interests. His notable expertise in Russian and Chinese military doctrines provides a strategic edge in crafting balanced and effective security strategies.

Mannina has held several prestigious positions, highlighting his commitment to national security. At Booz Allen Hamilton, he served as a Senior Advisor within the Joint Staff Chief Digital and Artificial Intelligence Office (CDAO). In this role, he was pivotal in modernizing the Department of Defense's Command and Control (C2) capabilities through the Joint All-Domain Command and Control (JADC2) initiative. His work facilitated the integration of cutting-edge digital and AI technologies into military operations, bolstering the U.S. defense posture.

Before his tenure at Booz Allen Hamilton, Mannina was a Special Agent for the Federal Bureau of Investigation, directing high-profile investigations into cyber espionage and illicit technology transfers. His proactive leadership in these investigations helped neutralize significant national security threats, particularly those emanating from technological espionage by adversarial nations.