Ok I'm annoying but I was reading through the last chapter updated, and Kisame mentions to Kuina how the whole Shinobi world knows of their relationship. Which led me to think Sasuke has to know at this point because it's been weeks at this point . So Itachi and Kisame leave the hideout and Kuina is by herself (also mentioned). My theory if the author were to ever come back is that she is kidnapped by Sasuke or his team he has at this point in the show and they use her as bait to lure Itachi in. Ultimately leaving him to have to choose between the love of his life OR his little brother. This gave me closure I won't comment again I PROMISE..bye ❤️