Rose was the cover athlete of NBA 2K13 alongside fellow NBA players Kevin Durant and Blake Griffin.
Rose was the lone cover athlete for the 2K Sports Downloadable Content game, NBA 2K10 Draft Combine, which was released on Xbox Live Arcade for the Xbox 360 and PlayStation Network for the PlayStation 3.
Rose is a part-owner and spokesman for the Chicago-based Giordano's Pizzeria.
In 2008, Rose signed a shoe deal with Adidas for $1 million per year.He has also signed with Wilson Sporting Goods.Other endorsement deals include Skullcandy headphones, Powerade, Force Factor sports drinks and a suburban Chicago Nissan dealership.In May 2018, it was announced that the Adidas D Rose 9's would be released in July 2018.
In 2011, Rose was estimated by Crain's Chicago Business to earn $1.5–$2.5 million annually in endorsements, ranking just outside the top 10 NBA players in that category.In 2012, it was reported that Rose signed a contract extension with Adidas, worth $185 million over 14 years.
