Sam: Whether it's a slight scratch, or something more serious, Sam completely withdraws into himself. He's come so far and done so well to leave his troubled past behind him, but one bruise on your body or break in your skin is enough to catapult him back into that turmoil. He won't say it, but you know what he's thinking; that it's his fault and that you'd be safer without him in your life. You've known a long time about the fear he harbours; that the people he loves will all meet a grizzly fate- just because they know him. He'll tend to your wounds in silence, with a grave expression on his face, avoiding your determined gaze. But as soon as he's finished you brush the medical supplies aside and take his face into your hands. You remind him gently of every time he's saved you from harm; the split seconds where he's pulled you out of danger's way, or the heart stopping moments he's risked himself to keep you safe. You spend as long as necessary convincing your troubled Winchester that he's not responsible for your injuries- you chose this life and all the risks that come with it. Eventually he'll give you a small, reluctant smile, and take hold of your hands and allow himself to see truth in what you're saying; he's the reason you manage to make it home alive every time.
_______________________________________________________Dean: The older Winchester tends to wear his heart on his sleeve, and his emotions are particularly close to the surface when you're involved. Dean's initial reaction to you being hurt is anger; a tense, jaw clenching rage. He's not angry with you of course, though sometimes you get caught on the end of a snippy remark. But it's the world that Dean resents so much. He's more than prepared to take on all the crap the universe seems to hurl his way- goodness knows he's been doing it long enough. But when the universe hurls crap at you? Well that's just too much. To Dean, you're the beacon of light he navigates his life with. When everything else is dark and twisted, you're by his side, pure and selfless and good. He knows of course, that there are many things in the world that are unjust, but he can't overlook the moments where the world decides to take things out on you. So he's angry at every demon, ghoul and vampire that thinks they have a right to touch you, and he's angry at himself, for failing to protect you. Luckily, you know Dean too damn well, and when you hobble into his room, with a bottle of beer in each hand and some goofy joke falling from your lips, his anger quickly dissolves. He'll pull you close, and simply hold you, eyes closed and arms strong as he remembers to silently thank the world. Because ultimately, he's just happy that you exist.
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Cas: The way Cas reacts to you getting hurt depends on what he can and can't do. Nine times out of ten, he can fix you up with a simple touch, and it's like you've never been hurt. Sometimes though, things aren't resolved so easily- whether you've been hurt by a cursed object that doesn't want to let you heal, or there's angel warding around blocking his celestial abilities- and Cas? Well, he tends to panic. He won't let you out of his sight- heck, he won't let you out of his arms. He'll hold you close to him, to prevent any further harm coming your way. He sure as hell won't let anyone touch you- not even Sam and Dean. He'll usher you away to somewhere safe and quiet, bombarding you with questions and apologies in a gruff voice. It often ends with you comforting him, instead of the other way round. Since his brief spell as a human though, he's at least become more practical. He knows now how to tend to injuries properly, and so he takes the time to thoroughly treat you, with all the right ointments and equipment. All the same, when he's done he'll still take you to some quiet corner. You'll both stay there for a while, chatting calmly while he watches you like a hawk. Cas is slowly coming to terms with the fact that even he can't fix every little thing that ails you, but he's more than ready to put in the time to care for you, with his beautiful, earnest nature. And secretly, you're kind of glad he worries about you so._________________________________________________________