Aniston is a supporter of Friends of El Faro, a grassroots non-profit organization that helps raise money for Casa Hogar Sion, an orphanage in Tijuana, Mexico. She has appeared in many TV commercials for St. Jude's Children's Research Hospital, which she supports. She also hosted September 2008's Stand Up to Cancer show. In the "It Can't Wait" campaign to free Burma, Aniston directed and starred in a video.
On April 14, 2007, Aniston received GLAAD's Vanguard Award for her contributions to increased visibility and understanding of the lesbian, gay, bisexual and transgender (LGBT) community. On Earth Day 2010, she joined Courteney Cox, Woody Harrelson, Ben Stiller and others, in "The Cove PSA: My Friend is...", an effort to stop the slaughter of dolphins and protect the Japanese people from the toxic levels of mercury found in dolphin meat. Other charities that Aniston has supported include AmeriCares, Clothes Off Our Back, Feeding America, EB Medical Research Foundation, Project A.L.S., OmniPeace, and Rape, Abuse & Incest National Network.
Aniston donated US$500,000 to Doctors Without Borders, Haitian health care provider Partners In Health andAmeriCares, and also participated in the Hope for Haiti Now telethon. In 2013, she was named theEntertainment Industry Foundation (EIF) ambassador for the Saks Fifth Avenue Key To The Cure campaign, which raises funds for the EIF Women's Cancer Research Fund to support research into the detection, treatment, and cures for women's cancers. In 2015, she supported the Comic Relief, Inc. charity.
In 2016, Aniston was honored by SmartWater for her ongoing philanthropic work for St. Jude's Children's Research Hospitalat a special event in LA for the hospital that was attended by numerous celebrities. During the event, Aniston spoke of the importance of philanthropy in her life to InStyle magazine stating, "We live an extremely beautiful, fortunate life being able to do what we get to do for a living. And so it's a way of being able to be in a position to do something for people who are less able. It’s something that makes my heart smile."
