Kyle Broflovski is a 17-year-old high school student who has a rare disease called "Flame Tears." Whenever he experiences intense emotions like hurt or betrayal, his eyes produce a fiery liquid that burns his face and surroundings. Kyle discovers this condition on his 12th birthday when his best friend Stan and his girlfriend(Stan's girlfriend)Wendy betray him. As a result, Kyle keeps to himself and only talks to a few friends, including Bebe, Clyde, Tweek, Butters, and some of the author's fanmade characters. The story explores Kyle's struggle to cope with his disease and the emotional trauma of being betrayed by his friends. As he tries to find a way to control his emotions, he discovers a mysterious group of people who also have unique abilities. Along the way, Kyle also learns to accept himself and his sexuality, even as he faces discrimination and prejudice from some of his classmates. As Kyle and his friends navigate through their personal struggles, they also face external threats and obstacles, including a group of bullies who target them, and a sinister organization that seeks to exploit their abilities. With the help of his friends, Kyle must find a way to overcome these challenges and protect himself and those he cares about.