For HONEY BUN, Darwin would've befriended Scrooge's enemies by accident.
Ma Beagle might attempt to adopt Darwin because she thinks he's better than the boys she had now.
Glomgold trying to make him his own nephew because he thought of Darwin as a mini version of him (tho, they're nothing alike)
Mark Beaks, not technically Scrooge's enemy, but Mark Beaks might used him for clout.