Obviously, there is nothing to change about Isaac. He is The all-around character. Even his Birthright, which is somewhat debatable since it's just Tainted Isaac's mechanic, and was something I gave quite a bit of thought about changing, possibly so that The D6 is just, moved to his consumable slot and nothing else. Upon reconsideration, that's a very bland change, even compared to his current one, and the current one just...fits, in a way. And that's kind of the thing with Isaac. Everything just fits about him. He's just right.
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The Binding of Isaac: Repentance Character Overhaul
RandomI did things with Isaac characters